RNAI TECHNOLOGY AND ITS APPLICATION-REVIEW

RNA interference (RNAi), an evolutionarily conserved mechanism triggered by double-stranded (dsRNA), causes gene silencing and inhibit translation in a sequence-specific manner. This technique was first time discovered Nematode Caenorhabditiselegans.The specificity robustness of RNAi have immense interest using as tool various settings which results intovarious significantachievements the area therapeutics, crop protection, production, weed management etc. Furthermore, it has found to potential controlling agricultural non pest such pathogen i.ebacteria, fungi & virus, insect nematodes. Moreover, leads theenhancement micronutrient or macronutrient bioavailability, improved salinity droughttolerance well enhanced resistance toextreme hot cold temperature tolerance.In this paper, we reviewed technology its then focused on applications agriculture biomedical research treatment for HIV, viral hepatitis several other diseases.